Control of human toxoplasmosis

نویسندگان

چکیده

• Toxoplasmosis is one of the most globally significant zoonotic diseases. Public health measures are critical but not sufficient to control toxoplasmosis. Several new anti- Toxoplasma chemotherapeutic targets have been identified. New immunotherapies and vaccines for toxoplasmosis promising experimental. Nanotechnologies could improve diagnosis delivery agents. caused by gondii, an apicomplexan parasite that able infect any nucleated cell in warm-blooded animal. gondii infects around 2 billion people and, whilst only a small percentage infected will suffer serious disease, prevalence makes it damaging diseases world. disease with multiple manifestations: can cause fatal encephalitis immunosuppressed people; if first contracted during pregnancy, miscarriage or congenital defects neonate; ocular even immunocompetent people. The has complex epidemiology, being transmitted ingestion oocysts shed faeces definitive feline hosts contaminate water, soil crops, consumption intracellular cysts undercooked meat from intermediate hosts. In this review we examine current future approaches toxoplasmosis, which encompass variety target different components life cycle T. . These include: education programs about avoidance contact infectious stages; biosecurity sanitation ensure food water safety; chemo- immunotherapeutics active infections disease; prophylactic options prevent acquisition infection livestock cyst formation meat; shedding

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ژورنال

عنوان ژورنال: International Journal for Parasitology

سال: 2021

ISSN: ['1879-0135', '0020-7519']

DOI: https://doi.org/10.1016/j.ijpara.2020.11.001